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  | | Protein-Nucleic Acid Interactions(1st Edition) Structural Biology (RSC Biomolecular Sciences) by Phoebe A. Rice, Carl C. Correll, Helen Berman, Renee Schroeder, Fred Dyda, Stefano Stella, John Heiss, Hong Li, Ronen Marmorstein, Manqing Hong, Catherine L. Lawson, Greg Van Duyne, Martin P. Horvath, Nancy C. Horton, Alison B. Hickman, Linda Jen-Jacobsen, Reid C. Johnson, James M. Berger, Ken Dong, Lewis A. Jacobson, Sabine Stampfl, Lukas Rajkowitsch, Katharina Semrad, Stephen Neidle, Simon Campbell, Marius Clore, Roderick E. Hubbard, Ian Moffatt Hardcover, 397 Pages, Published 2008 by Royal Society Of Chemistry ISBN-13: 978-0-85404-272-2, ISBN: 0-85404-272-5 "The structural biology of protein-nucleic acid interactions is in some ways a mature field and in others in its infancy. High-resolution structures of protein-DNA complexes have been studied since the mid 1980s and a vast array of such structures has now been determined, but surprising and novel structures still appear quite frequently. High-resolution structures of protein-RNA complexes were relatively rare until the last decade. ..." |
 | | Metabolomics, Metabonomics and Metabolite Profiling(1st Edition) RSC (RSC Biomolecular Sciences) by William J. Griffiths, Yuqin Wang, Stephen Neidle, Christian Ludwig, Xianlin Han, Tony Postle, Mark Viant, Richard Gross, Thomas Moritz, Eoin Fahy, Carlo Antonio, Sarah Robinson, Joao Rodrigues, Mark Fitzgerald, Caroline J. Earnshaw, Malcolm Clench, Cath Topliff, Marius Clore, Simon Campbell, Ulrich L. Gunther, Jane Thomas-Oates, Ian D. Wilson, Robert M. Barkley, Sally J. Atkinson, Michael Burrell, Annika I. Johansson, Anders Nordstrom, Jeremy K. Nicholson, Professor Robert Murphy Phd, Robert Murphy, Salway J.G. Hardcover, 336 Pages, Published 2007 by Royal Society Of Chemistry ISBN-13: 978-0-85404-299-9, ISBN: 0-85404-299-7 "The completion of gene sequencing has resulted in an intensified investigation of the proteome and metabolome. Metabolite profiling methods used for disease diagnosis have been expanded with the advent of new technology and are being applied extensively in the quest for the discovery of new markers for diseases. In this comprehensive resource, the Editor draws together experts from the field and provides an insightful introduction into ..." |
 | | Structural Virology(1st Edition) RSC (RSC Biomolecular Sciences) by Brittney Gurda, Robert Mckenna, Stephen Neidle, Timothy Baker, Lakshmanan Govindasamy, Nico Tjandra, John Domsic, Brian Bothner, Reza Khayat, Bentley Fane, Adam Zlotnick, Lindsay Black, Damian Ekiert, Thomas Smith, Bob Sinkovits, Rebecca Dutch, Eddy Arnold, Jack Johnson, Mark Young, Nicholas Muzyczka, Ben Dunn, Chuan Xiao, Mark Mckinlay, Mavis Agbandje-Mckenna, Colin Parrish, Ian Wilson, Alasdair C. Steven, Colin R. Parrish, Roderick E. Hubbard, Marius Clore, Simon Campbell, Mr Ian Wilson, John E. Johnson, Richard J. Samulski, Michael Rossmann, Mark Oram, Alexander Mcpherson, Mavisagbandje-Mckenna Hardcover, 388 Pages, Published 2010 by Royal Society Of Chemistry ISBN-13: 978-0-85404-171-8, ISBN: 0-85404-171-0 "Over the last ten years, much effort has been devoted to improving the biophysical techniques used in the study of viruses. This has resulted in the visualization of these large macromolecular assemblages at atomic level, thus providing the platform for functional interpretation and therapeutic design. Structural Virology covers a wide range of topics and is split into three sections. The first discusses the vast biophysical methodol ..." |
 | | Therapeutic Oligonucleotides(1st Edition) RSC (RSC Biomolecular Sciences) by Jens Kurreck, Troels Koch, Stephen Neidle, Eugen Uhlmann, C. A. Stein, Noah Kornblum, Sven Klubmann, Ben Berkhout, Johnathan Lai, Henry Fechner, Ian Maclachlan, John Rossi, Luba Benimetskaya, Martin Fabani, Jon Moulton, Markus Hecker, Gabriela Ivanova, Christoph Rosenbohm, Steffen, Simon Campbell, Marius Clore, Roderick E. Hubbard, Michael J. Gait, Hong M. Moulton, Nigel Courtenay-Luck, Donald M. Miller, Henrik F. Hansen, Bo Hansen, Ellen Marie Straarup, Sakari Kauppinen, Swen Wagner, Stefan W. Henning, Andreas H. Wagner, Dirk Eulberg, Werner Purschke, Hans-Joachim Anders, Norma Selve, Christian Reinsch, Evgenios Siepi, Andreas Dieckmann, Olivier Ter Brake, Lisa Scherer, Marco Weinberg Weinberg Hardcover, 343 Pages, Published 2008 by Royal Society Of Chemistry ISBN-13: 978-0-85404-116-9, ISBN: 0-85404-116-8 "This book provides a comprehensive overview of the development of therapeutic oligonucleotides for therapeutic applications, touching on a number of additional oligonucleotides including a number of small interfering RNAs currently in various phases of clinical development. Written by leading expert scientists from both academia and leading biotechnical companies, the authors provide a compelling update on current status of RNA inte ..." |
 | | Structural Biology of Membrane Proteins(1st Edition) RSC (RSC Biomolecular Sciences) by Susan K. Buchanan, Reinhard Grisshammer, Stephen Neidle, Gebhard Schertler, Filippo Mancia, Jean-Louis Baneres, Marius Clore, Simon Campbell, Philip J. Reeves, Reinhard K. Grisshammer, Tony Warne, Marc Baldus, Andreas Engel, Vinzenz Unger, Hartmut Lucke, Eduardo Perozo, Robert Stroud, Ian Collinson, Piet Gros, John H. Bushweller, Georg E. Schulz, Jesper V. Moller, Poul Nissen, Chris Tate, Petra Fromme, Eva Pebay-Peyroula, Dean Madden, Avinash Gill, Ben Luisi, Fabien Walas, Hiroyoshi Matsumura, Wayne A. Hendrickson, Tomasz Cierpicki, Yunpeng Zhou, Adam Lange, W. Kukulski, T. Kaufmann, T. Braun, H. Remigy, D. Fotiadis, John K. Lee, Shahram Khademi, David Savage, Ingo Grotjohann, Raimund Fromme Hardcover, 414 Pages, Published 2006 by Royal Society Of Chemistry ISBN-13: 978-0-85404-361-3, ISBN: 0-85404-361-6 "In the last few years there have been many exciting and innovative developments in the field of membrane protein structure and this trend is set to continue. Structural Biology of Membrane Proteins is a new monograph covering a wide range of topics with contributions from leading experts in the field. The book will be split into three sections: the first will discuss topics such as expression, purification and crystallisation; the se ..." |
 | | Nucleic Acid-Metal Ion Interactions by Nicholas V. Hud, Stephen Neidle, Loren Williams, Victoria Derose, Michael Brenowitz, Michael J. Schurr, Simon Campbell, Marius Clore, Janez Plavec Digital, 380 Pages, Published 2008 by Royal Society Of Chemistry ISBN-13: 978-1-84755-876-3, ISBN: 1-84755-876-3 "Natural biochemical processes are routinely being discovered in living cells that involve RNA. Some of these processes, such as RNA interference, are now being exploited for biotechnology and medicinal applications. DNA has also proven in recent years to be more than a passive storehouse of information. For example, non-B-form DNA structures formed by G-rich DNA have been shown to participate in the regulation of gene expression, a disc ..." |
 | | Hybrid Approaches to the Structural Biology of Macromolecular Complexes(1st Edition) (RSC Biomolecular Sciences) by Alasdair C. Steven, Stephen Neidle, Marius Clore, Roderick E. Hubbard Hardcover, 300 Pages, Published 2012 by Royal Society Of Chemistry ISBN-13: 978-1-84973-010-5, ISBN: 1-84973-010-5 "This reference will cover the interface between the chemical and biological sciences and focus on one of the key topics for the "Biomolecular Sciences" series, "Structural Biology". The book will deal with the structural analysis of living materials using techniques ranging from electron microscopy, imaging and crystallography to mass spectrometry and NMR. Illustrations of how these techniques are applied in living systems will be inclu ..." |
 | | Recent Developments in Biomolecular NMR by Marius Clore, Jennifer Potts 250 Pages, Published 2012 by Royal Society Of Chemistry ISBN-13: 978-1-84973-539-1, ISBN: 1-84973-539-5 "Marius Clore, Jennifer Potts. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. R. Godoy-Ruiz, C. Guo and V. Tugarinov , J. Am. Chem. Soc., 2010, 132, 18340–18350. R. L. Isaacson, P. J. Simpson, M. Liu, E. Cota, X. Zhang, P. Freemont and S. Matthews, J. Am. Chem. Soc., 2007, 129, 15428–15429. C. Amero, M. Asuncion Dura, M. Noirclerc-Savoye, A. Perollier, B. Gallet, M. J. Plevin, T. V ..." |
 | | RSC Biomolecular Sciences Biophysical Approaches Determining Ligand Binding to Biomolecular Targets 24 : Biomolecular Science Series Biophysical Approaches Determining Ligand Binding to Biomolecular Targets Volume 22 by Alberto Podjarny, Annick P. Dejaegere, Bruno Kieffer, Alain Van Dorsselaer, Daumantas Matulis, Stuart J. Khan, Stephen R. Martin, Stephen Neidle, Marius Clore Digital, 260 Pages, Published 2011 by Royal Society Of Chemistry ISBN-13: 978-1-84973-266-6, ISBN: 1-84973-266-3 "The binding of small ligands to biological molecules is central to most aspects of biological function. The past twenty years has seen the development of an increasing armoury of biophysical methods that not only detect such binding, but also provide varying degrees of information about the kinetics, thermodynamics and structural aspects of the process. These methods have received increasing attention with the growth in more rational ap ..." |
 | | Therapeutic Oligonucleotides by Jens Kurreck, Stephen Neidle, Michael J. Gait, Troels Koch, Eugen Uhlmann, Noah Kornblum, Simon Campbell, Marius Clore, C. A. Stein Digital, 362 Pages, Published 2008 by Royal Society Of Chemistry ISBN-13: 978-1-84755-827-5, ISBN: 1-84755-827-5 "This book provides a comprehensive overview of the development of therapeutic oligonucleotides for therapeutic applications, touching on a number of additional oligonucleotides including a number of small interfering RNAs currently in various phases of clinical development. Written by leading expert scientists from both academia and leading biotechnical companies, the authors provide a compelling update on current status of RNA interfer ..." |
 | | Sequence-Specific DNA Binding Agents by Michael J. Waring, Simon Campbell, K. R. Fox, David Rusling, Tom Brown, Yves Pommier, Dinshaw Patel, Marius Clore, Stephen Neidle Digital, 270 Pages, Published 2006 by Royal Society Of Chemistry ISBN-13: 978-1-84755-530-4, ISBN: 1-84755-530-6 "The binding of antibiotics and drugs to DNA is a fast developing area of research with important applications in medicine, particularly the treatment of cancer. Sequence-specific DNA Binding Agents uniquely discusses key aspects of this topic, providing a novel perspective on the subject. Written by experts in the field, this book discusses diverse modes of binding of antibiotics and drugs to DNA, emphasising matters that are important ..." |
 | | Nucleic Acid-Metal Ion Interactions(1st Edition) RSC (RSC Biomolecular Sciences) (2008-10-16) by Nicholas V. Hud, Loren Williams, Victoria Derose, Michael Brenowitz, Janez Plavec, Stephen Neidle, Adrian Parsegian, Bernhard Lippert, Richard Russell, Michael J. Schurr, Simon Campbell, Marius Clore, Joseph A. Piccirilli, Peter J. Sadler, David P. Giedroc, Richard Russell Che Hardcover, 433 Pages, Published 2008 by Royal Society Of Chemistry ISBN-13: 978-0-85404-195-4, ISBN: 0-85404-195-8 "Natural biochemical processes are routinely being discovered in living cells that involve RNA. Some of these processes, such as RNA interference, are now being exploited for biotechnology and medicinal applications. DNA has also proven in recent years to be more than a passive storehouse of information. For example, non-B-form DNA structures formed by G-rich DNA have been shown to participate in the regulation of gene expression, a disc ..." |
 | | (1st Edition) by Marius Clore, Jennifer Potts, Oliver Lange, Gerhard Wagner, Daniel Nietlispach, William Broadhurst, Marcellus Ubbink, Anthony Watts, Martin Blackledge, Jane H. Dyson, Jerome Boisbouvier, Gregg Siegal, Erik Zuiderweg, J. Patrick Loria, David Cowburn Hardcover, 347 Pages, Published 2012 by Royal Society Of Chemistry ISBN-13: 978-1-84973-120-1, ISBN: 1-84973-120-9 "NMR spectroscopy is widely used in biomolecular science particularly for structure determination of proteins, nucleic acids and carbohydrates. Much of the innovation within NMR spectroscopy has been within the field of protein NMR spectroscopy, an important technique in structural biology. Filling a gap in the literature, this book will draw together experts in the field to discuss the real advances in NMR methods that have occurred or ..." |
 | | DNA Conjugates and Sensors(1st Edition) RSC (RSC Biomolecular Sciences) by Tom Brown, Keith R. Fox, Duncan Graham, Makoto Komiyama, David Klenerman, Patrick Hrdlicka, Yingfu Li, Andrew Ellington, Souvik Maiti, Stephen Neidle, Yamuna Krishnan, Hiroyuki Asanuma, Peter G. Stockley, Roderick E. Hubbard, Marius Clore, Peter Stockley Hardcover, 316 Pages, Published 2012 by Royal Society Of Chemistry ISBN-13: 978-1-84973-427-1, ISBN: 1-84973-427-5 "Applications of nucleic acids have developed recently to provide solutions for biosensors, diagnostic tools and as platforms for the assembly of complex structures. These developments have been possible as their base sequence can be used to assemble precise structures following simple and predictable rules. Self-assembled DNA can then be amplified using polymerase chain reaction (PCR) and this ultimately enables the preparation of synth ..." |
 | | Biophysical Approaches Determining Ligand Binding to Biomolecular Targets(1st Edition) Detection, Measurement and Modelling (RSC Biomolecular Sciences) by Alberto Podjarny, Bruno Kieffer, Annick P. Dejaegere, Stephen Neidle, Alain Van Dorsselaer, Marius Clore, Roderick E. Hubbard, Daumantas Matulis, Wolfgang Jahnke, Yves Mely, Arne Schön, Stephen R. Martin, Jean-Michel Rondeau, Danièle Altschuh, Sarah Sanglier -Cianferani, Philip H. Howard, Dani Le Altschuh, Rsc Publishing, Goldfarb R.H., Daniþle Altschuh, Arne Sch N., Danile Altschuh Hardcover, 362 Pages, Published 2011 by Royal Society Of Chemistry ISBN-13: 978-1-84973-009-9, ISBN: 1-84973-009-1 "The binding of small ligands to biological molecules is central to most aspects of biological function. The past twenty years has seen the development of an increasing armoury of biophysical methods that not only detect such binding, but also provide varying degrees of information about the kinetics, thermodynamics and structural aspects of the process. These methods have received increasing attention with the growth in more rational ap ..." |
 | | 19(1st Edition) RNA Helicases: RSC (RSC Biomolecular Sciences) by Eckhard Jankowsky, Stephen Neidle, Scott Stevens, Patrick Linder, Mark Caprara, Haiwei Song, Roman Tuma, Marc Boudvillain, Karl-Peter Hopfner, William Chaplin Merrick, Marius Clore, Roderick E. Hubbard, Richard Russell Che, Anna Marie Pyle, Richard Russell, Athapol Noomhorm, Rick Russell, Dmitry V. Bavykin Hardcover, 304 Pages, Published 2010 by Royal Society Of Chemistry ISBN-13: 978-1-84755-914-2, ISBN: 1-84755-914-X "RNA helicases and RNA helicase-like proteins are the largest group of enzymes in eukaryotic RNA metabolism and although they are subject to intense ongoing research there is much confusion about function and classification of these enzymes. Although these enzymes are essential for virtually all processes involving RNA, there is no overview detailing structure, function and/or biological roles of these pivotal proteins. This book provide ..." |
 | | 20(1st Edition) Molecular Simulations and Biomembranes: From Biophysics to Function (RSC Biomolecular Sciences) by Philip Charles Biggin, Peter Tieleman, Ilpo Vattulainen, Stephen Neidle, Klaus Schulten, Syma Khalid, Emad Tajkhorshid, Philip C. Biggin, Benoit Roux, Marius Clore, Jonathan W. Essex, Martin B. Ulmschneider, Roderick E. Hubbard, Janice L. Robertson, Mark Sansom Hardcover, 353 Pages, Published 2010 by Royal Society Of Chemistry ISBN-13: 978-0-85404-189-3, ISBN: 0-85404-189-3 "The need for information in the understanding of membrane systems has been caused by three things - an increase in computer power; methodological developments and the recent expansion in the number of researchers working on it worldwide. However, there has been no up-to-date book that covers the application of simulation methods to membrane systems directly and this book fills an important void in the market. It provides a much neede ..." |
 | | Oxidative Folding of Peptides and Proteins(1st Edition) RSC (RSC Biomolecular Sciences) by Luis Moroder, Johannes Buchner, Grzegorz Bulaj, David Craik, Paul Alewood, Donald Hilvert, Knut Adermann, Wolfgang Haehnel, Neil Bulleid, D. Fass, Rudolf Glockshuber, Arne Holmgren, Ursula Jakob, Walter Neupert, Kleomenis Barlos, R. Rudolph, Jeannette Winter, John D. Wade, Stephen Neidle, Roderick E. Hubbard, Marius Clore, Rudolf K. Allemann, Dallas L. Rabenstein, R. B. Freedman, K. Hell, C. Lange, Matthias Johannes Feige, Katharina Gebendofer Hardcover, 448 Pages, Published 2009 by Royal Society Of Chemistry ISBN-13: 978-0-85404-148-0, ISBN: 0-85404-148-6 "The formation of disulfide bonds is probably the most influential modification of peptides and proteins. An elaborate set of cellular machinery exists to catalyze and guide this process. In recent years, significant developments have been made in both our understanding of the in vivo situation and the in vitro manipulation of disulfide bonds. This is the first monograph to provide a comprehensive overview of this exciting and rapidl ..." |
 | | Quantum Tunnelling in Enzyme-Catalysed Reactions(1st Edition) RSC (RSC Biomolecular Sciences) by Rudolf K. Allemann, Nigel S. Scrutton, Stephen Neidle, Donald G. Truhlar, Sharon Hammes-Schiffer, Barry Carpenter Obe, Roderick E. Hubbard, Marius Clore, Hanbin Liu, Mike Sutcliffe, Arieh Warshel, David Leys, Richard Schowen, Alexei Stuchebrukhov, Jiayun Pang, Sam Hay, Arundhuti Sen, Jiali Gao, Steven Y. Reece, Amnon Kohen, Shuhua Ma, Judith P. Klinman, R. A. Marcus, Daniel G. Nocera, Agnieszka Dybala-Defratyka, Piotr Paneth, Kin-Yiu Wong, Dan T. Major, Alessandro Cembran, Lingchun Song, Yen-Lin Lin, Yao Fan, E. Joel Loveridge, Contributor-Barry Carpenter, Rudolf Konrad Allemann Hardcover, 385 Pages, Published 2009 by Royal Society Of Chemistry ISBN-13: 978-0-85404-122-0, ISBN: 0-85404-122-2 "In recent years, there has been an explosion in knowledge and research associated with the field of enzyme catalysis and H-tunneling. Rich in its breath and depth, this introduction to modern theories and methods of study is suitable for experienced researchers those new to the subject. Edited by two leading experts, and bringing together the foremost practitioners in the field, this up-to-date account of a rapidly developing field ..." |
 | | RNA Polymerases as Molecular Motors(1st Edition) RSC (RSC Biomolecular Sciences) by Henri C. Buc, Terence Strick, Andrew Travers, Bianca Sclavi, Steve Block, G. Muskhelishvili, Achilles Kapanidis, Shimon Weiss, Tom Steitz, Konstantin Severinov, Evgeny Nudler, Robert Landick, Roger Kornberg, Michelle Wang, Jeff Gelles, Smita Patel, Steve Busby, Annie Kolb, Seth Darst, Natacha Opalka, Stephen Neidle, Marius Clore, Simon Campbell, E. P. Geiduschek, Jinwei Zhang, Lu Bai, Alla Shundrovsky, Carlos Bustamante, Thomas A. Steitz Hardcover, 331 Pages, Published 2009 by Royal Society Of Chemistry Illustrated ISBN-13: 978-0-85404-134-3, ISBN: 0-85404-134-6 "The cell can be viewed as a 'collection of protein machines' and understanding these molecular machines requires sophisticated cooperation between cell biologists, geneticists, enzymologists, crystallographers, chemists and physicists. To observe these machines in action, researchers have developed entirely new methodologies for the detection and the nanomanipulation of single molecules. This book, written by expert scientists in t ..." |