"The sequencing of the human genome and subsequent elucidation of the molecular pathways that are important in the pathology of disease have provided unprecedented opportunities for the development of new therapeutics. Nucleic acid-based drugs have emerged in recent years to yield extremely promising candidates for drug therapy to a wide range of diseases. Advances in Nucleic Acid Therapeutics is a comprehensive review of the latest adva ..."
"The structure, function and reactions of nucleic acids are central to molecular biology and are crucial for the understanding of complex biological processes involved. Revised and updated Nucleic Acids in Chemistry and Biology 3rd Edition discusses in detail, both the chemistry and biology of nucleic acids and brings RNA into parity with DNA. Written by leading experts, with extensive teaching experience, this new edition provides so ..."
"Since the discovery of the DNA double helix in 1953, nucleic acids have formed the central theme of much of contemporary molecular science. Recent mastery of nucleic acids synthesis has been the key to the establishment of the biotechnology industry, and our improving knowledge of nucleicacid structures and interactions is considerably influencing the design of novel drugs.The first edition of this book responded to the pressing need fo ..."
"This unique book takes a radically fresh approach in providing general information on the chemistry and biological activity of nucleic acids. The book is easily understood by those with a basic scientific background, and includes historical perspectives, an outline of essential features of DNA and RNA structure, and information on the chemical synthesis of biologically important nucleosides, nucleotides, and oligonucleotides. Nucleotid ..."
"Since the discovery of the DNA double helix in 1953, nucleic acids have formed the central theme of much of contemporary molecular science. Nowhere is this more apparent than in the increasing efforts to determine the DNA sequence of the human genome and the development of new diagnostics of genetic disease. Recent sophistication of nucleic acids synthesis has been key to the establishment of the biotechnology industry and our improving ..."
"This book provides a comprehensive overview of the development of therapeutic oligonucleotides for therapeutic applications, touching on a number of additional oligonucleotides including a number of small interfering RNAs currently in various phases of clinical development. Written by leading expert scientists from both academia and leading biotechnical companies, the authors provide a compelling update on current status of RNA inte ..."
"Ambati, T. A. Wilgus, L. A. DiPietro, e. Sakurai, k. Zhang, J. R. Smith, e. W. Taylor
and J. Ambati, Nature, 2008, 452, 591. S. Palchetti, D. Starace, P. De Cesaris, A.
Filippini, e. Ziparo and A. Riccioli, J. Biol. Chem., 2015, 290, 5470. M. Yu and ..."
"G Michael Blackburn, Michael J Gait, David Loakes, David M Williams. Preface.
The first edition of Nucleic Acids in Chemistry and Biology in 1990 met the
pressing need for a single volume that integrated the chemistry and biology of
nucleic acids in an introductory yet authoritative text. That book was so very well
received that in 1996 we ... In planning this third edition, we first expanded the
team of editors to include two youn ..."
"This unique book takes a radically fresh approach in providing general information on the chemistry and biological activity of nucleic acids. The book is easily understood by those with a basic scientific background, and includes historical perspectives, an outline of essential features of DNA and RNA structure, and information on the chemical synthesis of biologically important nucleosides, nucleotides, and oligonucleotides. Nucleotide ..."
"Oligonucleotides modulate gene-specific expression within cells and can be used to identify genes involved in diseases. Continuing developments in oligonucleotide research have begun to unleash their potential as therapeutic agents. Contributions from basic researchers in molecular biology, cell biology, nucleic acid chemistry, pharmacology, and applied therapeutics present new technologies in the field of oligonucleotide research and ..."
"This book features world renowned scholars and emerging voices that together open up the tradition of political theology to new ideas and new ways of thinking."