"The RSC Biomolecular Sciences Series is devoted to the coverage of the interface between the chemical and biological sciences, especially structural biology, chemical biology, bio- and chemo-informatics, drug discovery and development, chemical enzymology and biophysical chemistry. The RSC Biomolecular Sciences Sereis package, containing 20 of the leading series titles, offers a complete and definitive collection of reference and state- ..."
"R.X. Xu, A.M. Hassell, D.Vanderwall, M.H. Lambert, W.D. Holmes, M.A. Luther,
W.J. Rocque, M.V. Milburn, Y. Zhao, H. Ke and R.T. Nolte, Atomic structure of
PDE4: insights into phosphodiesterase mechanism and specificity, Science,
2000, 288(5472), 1822–1825. T. lglesias, R.T. Waldron and E. Rozengurt,
Identification of in Vivo ... J. Drenth, Principles of protein x-ray crystallography,
Springer-Verlag, NewYork Inc., 2002. J.P. Gluske ..."
"Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets. The first fragment-derived drug was recently approved for the treatment of melanoma. It is hoped that this approval is just the beginning of the many drugs yet to be discovered using this fascinating technique. This book is written ..."
"Drug discovery is a constantly developing and expanding area of research. Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry covers the past, present and future of the entire drug development process. Highlighting the recent successes and failures in drug discovery, the book helps readers to understand the factors governing modern drug discovery from the initial concept through to a marketed medicine. With c ..."