Caveolae and Lipid Rafts(1st Edition) Roles in Signal Transduction and the Pathogenesis of Human Disease, Volume 36 (Advances in Molecular and Cell Biology) by EdwardBittar, Philippe Frank, Michael Lisanti, ElsevierScience Hardcover, 264 Pages, Published 2005 by ElsevierScience ISBN-13: 978-0-444-51500-1, ISBN: 0-444-51500-3
"Caveolae (latin for little caves) are small structures found at the surface of cells. They are responsible for the regulation of important metabolic pathway. As a consequence, they may play a critical role in several human diseases such as atherosclerosis, cancer, diabetes, and muscular dystrophies. This book analyzes the role and function of caveolae in these aspects and serves as the first textbook currently available on caveolae/cave ..."
"It is now widely recognised that biological psychiatry is rapidly coming into its own. For over the last three decades dramatic advances in this young discipline have been made, all of which attest to the staying power of the experimental method. Those who made this revolution in knowledge happen are a breed of investigators availing themselves of the tools of molecular biology, pharmacology, genetics, and perhaps, above all, the techno ..."
"The seventh volume of a multi-volume work designed for medical students with rudimentary knowledge of cellular biology. It is the key discipline for the basic medical sciences and clinical medicine to be taught in an integrated curriculum. This text features developmental biology."
"This volume provides an overview of the cytoskeleton particularly on the fundamental role the cytoskeleton plays in the regulation of cell structure and function. This book represents new trends in cytoskeletal research that go beyond the traditional approach of identifying new proteins in the cytoskeleton, but actually define how these proteins interact with signaling pathways. While the major emphasis in this volume remains on the mic ..."
"Few cells conform to the stereotype of the spherical blob hastily scribbled on chalkboards and, regrettably, sometimes even displayed prominently in textbooks. Instead, real cells display a remarkable degree of structural and functional asymmetry. In modern cell biological parlance, this asymmetry has come to be lumped under the general heading of "cell polarity". Cell polarity is by no means restricted to the cells of tissues and organ ..."
"It should not come as too much of a surprise that biological membranes are considerably more complex than lipid bilayers. This has been made quite clear by the fluid-mosaic model which considers the cell membrane as a two-dimensional solution of a mosaic of integral membrane proteins and glycoproteins firmly embedded in a fluid lipid bilayer matrix. Such a model has several virtues, chief among which is that it allows membrane component ..."
"This volume is in two parts. The first contains the remaining chapters on cellular organelles and several chapters relating to organelle disorders. An account of mitochondriopathis is given in the chapter on the mitochondrion rather than in a separate one. The subject matter of this part of the volume shows quite clearly that the interdisciplinary approach to the study of organelles has shed considerable light on the nature of the mecha ..."
"This volume is intended to complete the Cell Chemistry and physiology module. It is about how the traditional boundaries of cell chemistry and physiology are being erased by molecular biology. We do not think it necessary to elaborate on this theme, particularly since the body of core knowledge found in this volume brings us a stage closer to answering the question, "what makes cell biology into a new discipline?"The first part of the v ..."
"This volume illustrates the extent to which the traditional distinction between biochemical and physiological processes is being obliterated by molecular biology. It can hardly be doubted that the revolution in cell and molecular biology is leading to core knowledge that provides an outline of the integrative and reductionist approach. We view this as the beginning of a new era, that of the integration of learning.As in the preceding vo ..."
Cell Chemistry and Physiology(1st Edition) Part I, Volume 4 (Principles of Medical Biology) by EdwardBittar, ElsevierScience Hardcover, 400 Pages, Published 1996 by ElsevierScience ISBN-13: 978-1-55938-805-4, ISBN: 1-55938-805-6
"This is the first of a 4-volume module that is an introduction to the study of cell chemistry and physiology. It is not intended to be encyclopedic in nature but rather a general survey of the subject with an emphasis on those topics that are central to an understanding of cell biology and those that are certain to become of increasing importance in the teaching of modern medicine.We have followed what appeared to as to be the logical d ..."
"Volume 1 of the series "Fundamentals of Medical Cell Biology" is devoted to evolutionary biology. This is presented in two parts: in the first, the structure and dynamics of RNA, DNA, and protein are dealt with. The second part is concerned with the origins and cellular basis of life."
"As a result of the key advances made more than 30 years ago, specifically the ability to isolate islets of Langerhans from the pancreas, the ability to measure insulin accurately by immunoasay, and the development of microchemical techniques for studying cells and their components, many research volumes, symposium reports, and original papers have been produced. This explosion of interest has probably had at least three stimuli:1. the ..."
"This readable, comprehensive text covers endothelial biology from the fundamentals of structure and lung fluid balance physiology to state-of-the-art descriptions of the molecular mechanisms involved in the development of lung failure. The material and illustrations, provided by outstanding experts in their individual areas of research and clinical concentration, is artfully woven together to provide the reader with an integrated, in-de ..."
The Liver in Biology and Disease, Volume 15(1st Edition) Liver Biology in Disease, Hepato - Biology in Disease (Principles of Medical Biology) by EdwardBittar, Ricardo Bittar Hardcover, 600 Pages, Published 2005 by ElsevierScience ISBN-13: 978-0-7623-1124-8, ISBN: 0-7623-1124-X
"The Liver in Biology and Disease was conceived as a sequel in the series Principles of Medical Biology, whose general aim continues to be the integration of human biology and molecular cell biology into modern molecular medicine. It is a volume molded by the Information Revolution which few will deny has forced the teaching faculties in our medical schools to curtail and prune the teaching load and focus on fundamentals and principles. ..."
Microbiology(1st Edition) (Principles of Medical Biology) by EdwardBittar, Neville Bittar Hardcover, 404 Pages, Published 1998 by ElsevierScience ISBN-13: 978-1-55938-814-6, ISBN: 1-55938-814-5
"There is a need in small group teaching for a readable module that provides a balanced treatment of the four main areas of medical microbiology-bacteriology, mycology, virology and parasistology. It need not be encyclopedic in scope nor didactic, but it should emphasise principles and concepts. Any existing gaps in this type of presentation are, of course, left for the student to fill.Some subject material has been excluded. An example ..."
"The present volume is the first in the advances in oncobiology series. It is meant to be useful not only to clinical and non-clinical oncologists but also to graduate students and medical students. The individual chapters are presented as self-contained summaries of current knowledge rather than as reviews. The last chapter deals with the subject of chemotherapy."
Cell Chemistry and Physiology(1st Edition) Part III, Volume 4C (Principles of Medical Biology) by EdwardBittar, Neville Bittar Hardcover, 361 Pages, Published 1996 by ElsevierScience ISBN-13: 978-1-55938-807-8, ISBN: 1-55938-807-2
"The first section of this volume consists of five chapters to the nature of membrane transport systems. A chapter on secondary active glucose transport has been omitted because this topic is slated to appear in the Nephrobiology module. Chapter 6 deals with oxidase control of plasma membrane proton transport, while chapter 7 addresses the question of how cell volume is regulated. Although we chose not to have a separate chapter covering ..."
"The tools of molecular biology have revolutionised our understanding of gene structure and function and changed the teaching of genetics in a fundamental way. The transition from classical genetics to molecular genetics was initiated by two discoveries. One was the discovery that DNA has a complementary double helix structure and the other that a universal genetic code does exist. Both led to the acceptance of the central dogma that RNA ..."
"Volume 1 of the series "Fundamentals of Medical Cell Biology" is devoted to evolutionary biology. This is presented in two parts: in the first, the structure and dynamics of RNA, DNA, and protein are dealt with. The second part is concerned with the origins and cellular basis of life."
"The present volume represents an effort at presenting the subject of membrane biochemistry and the organization and dynamics of subcellular organelles in an exciting and somewhat tentative manner. Tentative in the sense that facts and theories are often kept clear and distinct, and alternative ways of thinking are suggested. Thus, if the thoughtful student not only comprehends the significance of this subject, but goes on to develop an ..."